Evidence for linkage of pfmdr1, pfcrt, and pfk13 polymorphisms to lumefantrine and mefloquine susceptibilities in a Plasmodium falciparum cross

BACKGROUND: Lumefantrine and mefloquine are used worldwide in artemisinin-based combination therapy (ACT) of malaria. Better understanding of drug susceptibility and resistance is needed and can be obtained from studies of genetic crosses. METHODS: Drug response phenotypes of a cross between Plasmod...

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Détails bibliographiques
Publié dans:Int J Parasitol Drugs Drug Resist
Auteurs principaux: Windle, Sean T., Lane, Kristin D., Gadalla, Nahla B., Liu, Anna, Mu, Jianbing, Caleon, Ramoncito L., Rahman, Rifat S., Sá, Juliana M., Wellems, Thomas E.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7677662/
https://ncbi.nlm.nih.gov/pubmed/33197753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2020.10.009
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