Prevalence of Plasmodium falciparum anti-malarial resistance-associated polymorphisms in pfcrt, pfmdr1 and pfnhe1 in Muheza, Tanzania, prior to introduction of artemisinin combination therapy

BACKGROUND: A report of the chloroquine and amodiaquine resistance pfcrt-SVMNT haplotype in Tanzania raises concern about high-level resistance to the artesunate-amodiaquine combination treatment widely employed in Africa. Mutations in the pfmdr1 multi-drug resistance gene may also be associated wit...

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Detalles Bibliográficos
Publicado en:Malar J
Main Authors: Gadalla, Nahla B, Tavera, Gloria, Mu, Jianbing, Kabyemela, Edward R, Fried, Michael, Duffy, Patrick E, Sá, Juliana M, Wellems, Thomas E
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392636/
https://ncbi.nlm.nih.gov/pubmed/25890383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-0642-2
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