In vitro selection of Plasmodium falciparum Pfcrt and Pfmdr1 variants by artemisinin

BACKGROUND: Anti-malarial drugs are the major focus in the prevention and treatment of malaria. Artemisinin-based combination therapy (ACT) is the WHO recommended first-line treatment for Plasmodium falciparum malaria across the endemic world. Also ACT is increasingly relied upon in treating Plasmod...

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Udgivet i:Malar J
Main Authors: Njokah, Muturi J., Kang’ethe, Joseph N., Kinyua, Johnson, Kariuki, Daniel, Kimani, Francis T.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957835/
https://ncbi.nlm.nih.gov/pubmed/27449110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1443-y
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