In Vitro Activities of Piperaquine, Lumefantrine, and Dihydroartemisinin in Kenyan Plasmodium falciparum Isolates and Polymorphisms in pfcrt and pfmdr1

We have analyzed the in vitro chemosensitivity profiles of 115 Kenyan isolates for chloroquine (CQ), piperaquine, lumefantrine (LM), and dihydroartemisinin in association with polymorphisms in pfcrt at codon 76 and pfmdr1 at codon 86, as well as with variations of the copy number of pfmdr1. The medi...

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Detalhes bibliográficos
Main Authors: Mwai, Leah, Kiara, Steven M., Abdirahman, Abdi, Pole, Lewa, Rippert, Anja, Diriye, Abdi, Bull, Pete, Marsh, Kevin, Borrmann, Steffen, Nzila, Alexis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786317/
https://ncbi.nlm.nih.gov/pubmed/19770282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00638-09
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