The Role of Pfmdr1 and Pfcrt in Changing Chloroquine, Amodiaquine, Mefloquine and Lumefantrine Susceptibility in Western-Kenya P. falciparum Samples during 2008–2011

Single Nucleotide Polymorphisms (SNPs) in the Pfmdr1, and Pfcrt, genes of Plasmodium falciparum may confer resistance to a number of anti-malaria drugs. Pfmdr1 86Y and haplotypes at Pfcrt 72-76 have been linked to chloroquine (CQ) as well as amodiaquine (AQ) resistance. mefloquine (MQ) and lumefantr...

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Bibliografiska uppgifter
Huvudupphovsmän: Eyase, Fredrick L., Akala, Hoseah M., Ingasia, Luiser, Cheruiyot, Agnes, Omondi, Angela, Okudo, Charles, Juma, Dennis, Yeda, Redemptah, Andagalu, Ben, Wanja, Elizabeth, Kamau, Edwin, Schnabel, David, Bulimo, Wallace, Waters, Norman C., Walsh, Douglas S., Johnson, Jacob D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652850/
https://ncbi.nlm.nih.gov/pubmed/23675533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064299
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