Analysis of Major Genome Loci Underlying Artemisinin Resistance and pfmdr1 Copy Number in pre- and post-ACTs in Western Kenya

Genetic analysis of molecular markers is critical in tracking the emergence and/or spread of artemisinin resistant parasites. Clinical isolates collected in western Kenya pre- and post- introduction of artemisinin combination therapies (ACTs) were genotyped at SNP positions in regions of strong sele...

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Udgivet i:Sci Rep
Main Authors: Ngalah, Bidii S., Ingasia, Luiser A., Cheruiyot, Agnes C., Chebon, Lorna J., Juma, Dennis W., Muiruri, Peninah, Onyango, Irene, Ogony, Jack, Yeda, Redemptah A., Cheruiyot, Jelagat, Mbuba, Emmanuel, Mwangoka, Grace, Achieng, Angela O., Ng'ang'a, Zipporah, Andagalu, Ben, Akala, Hoseah M., Kamau, Edwin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319159/
https://ncbi.nlm.nih.gov/pubmed/25655315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08308
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