Analysis of Major Genome Loci Underlying Artemisinin Resistance and pfmdr1 Copy Number in pre- and post-ACTs in Western Kenya

Genetic analysis of molecular markers is critical in tracking the emergence and/or spread of artemisinin resistant parasites. Clinical isolates collected in western Kenya pre- and post- introduction of artemisinin combination therapies (ACTs) were genotyped at SNP positions in regions of strong sele...

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Publicado en:Sci Rep
Autores principales: Ngalah, Bidii S., Ingasia, Luiser A., Cheruiyot, Agnes C., Chebon, Lorna J., Juma, Dennis W., Muiruri, Peninah, Onyango, Irene, Ogony, Jack, Yeda, Redemptah A., Cheruiyot, Jelagat, Mbuba, Emmanuel, Mwangoka, Grace, Achieng, Angela O., Ng'ang'a, Zipporah, Andagalu, Ben, Akala, Hoseah M., Kamau, Edwin
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319159/
https://ncbi.nlm.nih.gov/pubmed/25655315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08308
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