Integration of whole-exome and anchored PCR-based next generation sequencing significantly increases detection of actionable alterations in precision oncology

BACKGROUND: Frequency of clinically relevant mutations in solid tumors by targeted and whole-exome sequencing is ∼30%. Transcriptome analysis complements detection of actionable gene fusions in advanced cancer patients. Goal of this study was to determine the added value of anchored multiplex PCR (A...

詳細記述

保存先:
書誌詳細
出版年:Transl Oncol
主要な著者: Beg, Shaham, Bareja, Rohan, Ohara, Kentaro, Eng, Kenneth Wha, Wilkes, David C., Pisapia, David J., Zoughbi, Wael Al, Kudman, Sarah, Zhang, Wei, Rao, Rema, Manohar, Jyothi, Kane, Troy, Sigouros, Michael, Xiang, Jenny Zhaoying, Khani, Francesca, Robinson, Brian D., Faltas, Bishoy M., Sternberg, Cora N., Sboner, Andrea, Beltran, Himisha, Elemento, Olivier, Mosquera, Juan Miguel
フォーマット: Artigo
言語:Inglês
出版事項: Neoplasia Press 2020
主題:
Original article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674614/
https://ncbi.nlm.nih.gov/pubmed/33190043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100944
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料