Cancer-Specific Thresholds Adjust for Whole Exome Sequencing–Based Tumor Mutational Burden Distribution

PURPOSE: To understand the clinical context of tumor mutational burden (TMB) when comparing a pan-cancer threshold and a cancer-specific threshold. MATERIALS AND METHODS: Using whole exome sequencing data from primary tumors in The Cancer Genome Atlas (n = 3,534) and advanced and/or metastatic tumor...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:JCO Precis Oncol
Main Authors: Fernandez, Evan M., Eng, Kenneth, Beg, Shaham, Beltran, Himisha, Faltas, Bishoy M., Mosquera, Juan Miguel, Nanus, David M., Pisapia, David J., Rao, Rema A., Robinson, Brian D., Rubin, Mark A., Elemento, Olivier, Sboner, Andrea, Shah, Manish A., Song, Wei
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Clinical Oncology 2019
Fag:
Original Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6716608/
https://ncbi.nlm.nih.gov/pubmed/31475242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.18.00400
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker