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InhA inhibitors have activity against non-replicating Mycobacterium tuberculosis

We previously identified a diazaborine series with potential for development as a new tuberculosis drug. This series has activity in vitro and in vivo and targets cell wall biosynthesis via inhibition of InhA. The overall aim of this study was to determine whether InhA inhibitors have activity again...

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Bibliographic Details
Published in:PLoS One
Main Authors: Flint, Lindsay, Korkegian, Aaron, Parish, Tanya
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671525/
https://ncbi.nlm.nih.gov/pubmed/33201882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239354
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