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InhA inhibitors have activity against non-replicating Mycobacterium tuberculosis

We previously identified a diazaborine series with potential for development as a new tuberculosis drug. This series has activity in vitro and in vivo and targets cell wall biosynthesis via inhibition of InhA. The overall aim of this study was to determine whether InhA inhibitors have activity again...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Flint, Lindsay, Korkegian, Aaron, Parish, Tanya
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671525/
https://ncbi.nlm.nih.gov/pubmed/33201882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239354
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