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Mechanisms of resistance against NITD-916, a direct inhibitor of Mycobacterium tuberculosis InhA
Isoniazid inhibits Mycobacterium tuberculosis InhA and is a key component of drug regimens that treat tuberculosis. However, the high rate of resistance against isoniazid is a contributing factor to the emergence of multi-drug resistance strains of M. tuberculosis. The 4-hydroxy-2-pyridine NITD-916...
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| 出版年: | Tuberculosis (Edinb) |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5679704/ https://ncbi.nlm.nih.gov/pubmed/29050761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2017.09.003 |
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