Linsitinib (OSI-906) antagonizes ATP-binding cassette subfamily G member 2 and subfamily C member 10-mediated drug resistance

In this study we investigated the effect of linsitinib on the reversal of multidrug resistance (MDR) mediated by the overexpression of the ATP-binding cassette (ABC) subfamily members ABCB1, ABCG2, ABCC1 and ABCC10. Our results indicate for the first time that linsitinib significantly potentiate the...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Int J Biochem Cell Biol
Autors principals: Zhang, Hui, Kathawala, Rishil J., Wang, Yi-Jun, Zhang, Yun-Kai, Patel, Atish, Shukla, Suneet, Robey, Robert W., Talele, Tanaji T., Ashby, Charles R., Ambudkar, Suresh V., Bates, Susan E., Fu, Li-Wu, Chen, Zhe-Sheng
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7670583/
https://ncbi.nlm.nih.gov/pubmed/24726739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2014.03.026
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars