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Intrinsic and Extrinsic Programming of Product Chain Length and Release Mode in Fungal Collaborating Iterative Polyketide Synthases
Combinatorial biosynthesis with fungal polyketide synthases (PKSs) promises to produce unprecedented bioactive “unnatural” natural products (uNPs) for drug discovery. Genome mining of the dothideomycete Rhytidhysteron rufulum uncovered a collaborating highly reducing PKS (hrPKS) – nonreducing PKS (n...
Gorde:
| Argitaratua izan da: | J Am Chem Soc |
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| Egile Nagusiak: | , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7659983/ https://ncbi.nlm.nih.gov/pubmed/32833442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c07050 |
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