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Thioesterase Domains of Fungal Nonreducing Polyketide Synthases Act as Decision Gates during Combinatorial Biosynthesis

A crucial step during the programmed biosynthesis of fungal polyketide natural products is the release of the final polyketide intermediate from the iterative polyketide synthases (iPKSs), most frequently by a thioesterase (TE) domain. Realization of combinatorial biosynthesis with iPKSs requires TE...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Xu, Yuquan, Zhou, Tong, Zhang, Shuwei, Xuan, Li-Jiang, Zhan, Jixun, Molnár, István
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780601/
https://ncbi.nlm.nih.gov/pubmed/23822773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4041362
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