Diversity-oriented combinatorial biosynthesis of benzenediol lactone scaffolds by subunit shuffling of fungal polyketide synthases

Combinatorial biosynthesis aspires to exploit the promiscuity of microbial anabolic pathways to engineer the synthesis of new chemical entities. Fungal benzenediol lactone (BDL) polyketides are important pharmacophores with wide-ranging bioactivities, including heat shock response and immune system...

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Detaylı Bibliyografya
Asıl Yazarlar: Xu, Yuquan, Zhou, Tong, Zhang, Shuwei, Espinosa-Artiles, Patricia, Wang, Luoyi, Zhang, Wei, Lin, Min, Gunatilaka, A. A. Leslie, Zhan, Jixun, Molnár, István
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2014
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151742/
https://ncbi.nlm.nih.gov/pubmed/25049383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406999111
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