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Investigation of fungal iterative polyketide synthase functions using partially assembled intermediates
Iterative polyketide synthases (PKS) are large multifunctional enzymes that resemble eukaryotic fatty acid synthases, but can make highly functionalized secondary metabolites using complex and unresolved programming rules. During biosynthesis of the kinase inhibitor hypothemycin by Hypomyces subicul...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3577055/ https://ncbi.nlm.nih.gov/pubmed/23356934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4001823 |
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