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Investigation of fungal iterative polyketide synthase functions using partially assembled intermediates

Iterative polyketide synthases (PKS) are large multifunctional enzymes that resemble eukaryotic fatty acid synthases, but can make highly functionalized secondary metabolites using complex and unresolved programming rules. During biosynthesis of the kinase inhibitor hypothemycin by Hypomyces subicul...

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Sonraí Bibleagrafaíochta
Main Authors: Gao, Zhizeng, Wang, Jingjing, Norquay, Amy K., Qiao, Kangjian, Tang, Yi, Vederas, John C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577055/
https://ncbi.nlm.nih.gov/pubmed/23356934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4001823
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