Sensitivity and kinase activity of epidermal growth factor receptor (EGFR) exon 19 and others to EGFR‐tyrosine kinase inhibitors

The presence of epidermal growth factor receptor (EGFR) somatic mutations in non‐small‐cell lung cancer patients is associated with response to treatment with EGFR‐tyrosine kinase inhibitors, such as gefitinib and erlotinib. More than 100 mutations in the kinase domain of EGFR have been identified....

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Furuyama, Kazuto, Harada, Taishi, Iwama, Eiji, Shiraishi, Yoshimasa, Okamura, Kyoko, Ijichi, Kayo, Fujii, Akiko, Ota, Keiichi, Wang, Shuo, Li, Heyan, Takayama, Koichi, Giaccone, Giuseppe, Nakanishi, Yoichi
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2013
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657170/
https://ncbi.nlm.nih.gov/pubmed/23387505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12125
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