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Development of anaplastic lymphoma kinase (ALK) inhibitors and molecular diagnosis in ALK rearrangement-positive lung cancer
The fusion of echinoderm microtubule-associated protein-like 4 with anaplastic lymphoma kinase (ALK) was identified as a transforming gene for lung cancer in 2007. This genetic rearrangement accounts for 2%–5% of non-small-cell lung cancer (NSCLC) cases, occurring predominantly in younger individual...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Dove Medical Press
2014
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949762/ https://ncbi.nlm.nih.gov/pubmed/24623980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S38868 |
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