Precision therapy with anaplastic lymphoma kinase inhibitor ceritinib in ALK-rearranged anaplastic large cell lymphoma

BACKGROUND: More than 80% of anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma (ALCL) patients harbor the (nucleophosmin) NPM1-ALK fusion gene t(2;5) chromosomal translocation. We evaluated the preclinical and clinical efficacy of ceritinib treatment of this aggressive lymphom...

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Bibliografiske detaljer
Udgivet i:ESMO Open
Main Authors: Subbiah, V., Kuravi, S., Ganguly, S., Welch, D.R., Vivian, C.J., Mushtaq, M.U., Hegde, A., Iyer, S., Behrang, A., Ali, S.M., Madison, R.W., Venstrom, J.M., Jensen, R.A., McGuirk, J.P., Amin, H.M., Balusu, R.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8271116/
https://ncbi.nlm.nih.gov/pubmed/34242968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.esmoop.2021.100172
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