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Sensitivity and kinase activity of epidermal growth factor receptor (EGFR) exon 19 and others to EGFR‐tyrosine kinase inhibitors

The presence of epidermal growth factor receptor (EGFR) somatic mutations in non‐small‐cell lung cancer patients is associated with response to treatment with EGFR‐tyrosine kinase inhibitors, such as gefitinib and erlotinib. More than 100 mutations in the kinase domain of EGFR have been identified....

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Podrobná bibliografie
Vydáno v:Cancer Sci
Hlavní autoři: Furuyama, Kazuto, Harada, Taishi, Iwama, Eiji, Shiraishi, Yoshimasa, Okamura, Kyoko, Ijichi, Kayo, Fujii, Akiko, Ota, Keiichi, Wang, Shuo, Li, Heyan, Takayama, Koichi, Giaccone, Giuseppe, Nakanishi, Yoichi
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657170/
https://ncbi.nlm.nih.gov/pubmed/23387505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12125
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