Sensitivity and kinase activity of epidermal growth factor receptor (EGFR) exon 19 and others to EGFR‐tyrosine kinase inhibitors

The presence of epidermal growth factor receptor (EGFR) somatic mutations in non‐small‐cell lung cancer patients is associated with response to treatment with EGFR‐tyrosine kinase inhibitors, such as gefitinib and erlotinib. More than 100 mutations in the kinase domain of EGFR have been identified....

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Furuyama, Kazuto, Harada, Taishi, Iwama, Eiji, Shiraishi, Yoshimasa, Okamura, Kyoko, Ijichi, Kayo, Fujii, Akiko, Ota, Keiichi, Wang, Shuo, Li, Heyan, Takayama, Koichi, Giaccone, Giuseppe, Nakanishi, Yoichi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657170/
https://ncbi.nlm.nih.gov/pubmed/23387505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12125
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