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Sensitivity and kinase activity of epidermal growth factor receptor (EGFR) exon 19 and others to EGFR‐tyrosine kinase inhibitors

The presence of epidermal growth factor receptor (EGFR) somatic mutations in non‐small‐cell lung cancer patients is associated with response to treatment with EGFR‐tyrosine kinase inhibitors, such as gefitinib and erlotinib. More than 100 mutations in the kinase domain of EGFR have been identified....

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Furuyama, Kazuto, Harada, Taishi, Iwama, Eiji, Shiraishi, Yoshimasa, Okamura, Kyoko, Ijichi, Kayo, Fujii, Akiko, Ota, Keiichi, Wang, Shuo, Li, Heyan, Takayama, Koichi, Giaccone, Giuseppe, Nakanishi, Yoichi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657170/
https://ncbi.nlm.nih.gov/pubmed/23387505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12125
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