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Highly sensitive and quantitative evaluation of the EGFR T790M mutation by nanofluidic digital PCR

The mutation of T790M in EGFR is a major mechanism of resistance to treatment with EGFR-TKIs. Only qualitative detection (presence or absence) of T790M has been described to date, however. Digital PCR (dPCR) analysis has recently been applied to the quantitative detection of target molecules in canc...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Iwama, Eiji, Takayama, Koichi, Harada, Taishi, Okamoto, Isamu, Ookubo, Fumihiko, Kishimoto, Junji, Baba, Eishi, Oda, Yoshinao, Nakanishi, Yoichi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653018/
https://ncbi.nlm.nih.gov/pubmed/26015401
Tagiau: Ychwanegu Tag
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