Highly sensitive and quantitative evaluation of the EGFR T790M mutation by nanofluidic digital PCR

The mutation of T790M in EGFR is a major mechanism of resistance to treatment with EGFR-TKIs. Only qualitative detection (presence or absence) of T790M has been described to date, however. Digital PCR (dPCR) analysis has recently been applied to the quantitative detection of target molecules in canc...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Iwama, Eiji, Takayama, Koichi, Harada, Taishi, Okamoto, Isamu, Ookubo, Fumihiko, Kishimoto, Junji, Baba, Eishi, Oda, Yoshinao, Nakanishi, Yoichi
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653018/
https://ncbi.nlm.nih.gov/pubmed/26015401
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