Zmat3 is a key splicing regulator in the p53 tumor suppression program

Although TP53 is the most commonly mutated gene in human cancers, the p53-dependent transcriptional programs mediating tumor suppression remain incompletely understood. Here, to uncover critical components downstream of p53 in tumor suppression, we perform unbiased RNAi and CRISPR/Cas9-based genetic...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Bieging-Rolett, Kathryn T., Kaiser, Alyssa, Morgens, David W., Boutelle, Anthony M., Seoane, Jose A., Van Nostrand, Eric L., Zhu, Changyu, Houlihan, Shauna L., Mello, Stephano S., Yee, Brian A., McClendon, Jacob, Pierce, Sarah E., Winters, Ian P., Wang, Mengxiong, Connolly, Andrew J., Lowe, Scott W., Curtis, Christina, Yeo, Gene W., Winslow, Monte M., Bassik, Michael C., Attardi, Laura D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654708/
https://ncbi.nlm.nih.gov/pubmed/33157015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.10.022
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