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p53 deficiency triggers dysregulation of diverse cellular processes in physiological oxygen

The mechanisms by which TP53, the most frequently mutated gene in human cancer, suppresses tumorigenesis remain unclear. p53 modulates various cellular processes, such as apoptosis and proliferation, which has led to distinct cellular mechanisms being proposed for p53-mediated tumor suppression in d...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Valente, Liz J., Tarangelo, Amy, Li, Albert Mao, Naciri, Marwan, Raj, Nitin, Boutelle, Anthony M., Li, Yang, Mello, Stephano Spano, Bieging-Rolett, Kathryn, DeBerardinis, Ralph J., Ye, Jiangbin, Dixon, Scott J., Attardi, Laura D.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594498/
https://ncbi.nlm.nih.gov/pubmed/32886745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201908212
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