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p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells

How cancer cells respond to nutrient deprivation remains poorly understood. In certain cancer cells, deprivation of cystine induces a non-apoptotic, iron-dependent form of cell death termed ferroptosis. Recent evidence suggests that ferroptosis sensitivity may be modulated by the stress-responsive t...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Tarangelo, Amy, Magtanong, Leslie, Bieging-Rolett, Kathryn T., Li, Yang, Ye, Jiangbin, Attardi, Laura D., Dixon, Scott J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791910/
https://ncbi.nlm.nih.gov/pubmed/29346757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.12.077
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