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Discovery of Benzyl Tetraphosphonate Derivative as Inhibitor of Human Factor Xia
The inhibition of factor XIa (FXIa) is a trending paradigm for the development of new generations of anticoagulants without a substantial risk of bleeding. In this report, we present the discovery of a benzyl tetra‐phosphonate derivative as a potent and selective inhibitor of human FXIa. Biochemical...
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| Publicado en: | ChemistryOpen |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7654249/ https://ncbi.nlm.nih.gov/pubmed/33204588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.202000277 |
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