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Sulfonated Nonsaccharide Heparin Mimetics Are Potent and Noncompetitive Inhibitors of Human Neutrophil Elastase
[Image: see text] Human neutrophil elastase (HNE) is a serine protease that plays vital roles in inflammation, innate immune response, and tissue remodeling processes. HNE has been actively pursued as a drug target, particularly for the treatment of cardiopulmonary diseases. Although thousands of mo...
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| Pubblicato in: | ACS Omega |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical Society
2021
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8154244/ https://ncbi.nlm.nih.gov/pubmed/34056422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.1c00935 |
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