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Discovery of Benzyl Tetraphosphonate Derivative as Inhibitor of Human Factor Xia
The inhibition of factor XIa (FXIa) is a trending paradigm for the development of new generations of anticoagulants without a substantial risk of bleeding. In this report, we present the discovery of a benzyl tetra‐phosphonate derivative as a potent and selective inhibitor of human FXIa. Biochemical...
Tallennettuna:
| Julkaisussa: | ChemistryOpen |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
John Wiley and Sons Inc.
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7654249/ https://ncbi.nlm.nih.gov/pubmed/33204588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.202000277 |
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