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Recent Advances in the Discovery and Development of Factor XI/XIa Inhibitors

Factor XIa (FXIa) is a serine protease homodimer that belongs to the intrinsic coagulation pathway. FXIa primarily catalyzes factor IX activation to factor IXa which subsequently activates factor X to factor Xa in the common coagulation pathway. Growing evidence suggests that FXIa plays an important...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Med Res Rev
Prif Awduron: Al-Horani, Rami A., Afosah, Daniel K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173998/
https://ncbi.nlm.nih.gov/pubmed/29727017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/med.21503
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