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Recent Advances in the Discovery and Development of Factor XI/XIa Inhibitors
Factor XIa (FXIa) is a serine protease homodimer that belongs to the intrinsic coagulation pathway. FXIa primarily catalyzes factor IX activation to factor IXa which subsequently activates factor X to factor Xa in the common coagulation pathway. Growing evidence suggests that FXIa plays an important...
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| Publicado en: | Med Res Rev |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6173998/ https://ncbi.nlm.nih.gov/pubmed/29727017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/med.21503 |
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