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Factor XIIIa Inhibitors as Potential Novel Drugs for Venous Thromboembolism
Human factor XIIIa (FXIIIa) is a multifunctional transglutaminase with a significant role in hemostasis. FXIIIa catalyzes the last step in the coagulation process. It stabilizes the blood clot by cross-linking the α- and γ-chains of fibrin. It also protects the newly formed clot from plasmin-mediate...
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| Argitaratua izan da: | Eur J Med Chem |
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| Egile Nagusiak: | , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7513741/ https://ncbi.nlm.nih.gov/pubmed/32502864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.112442 |
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