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Factor XIIIa Inhibitors as Potential Novel Drugs for Venous Thromboembolism

Human factor XIIIa (FXIIIa) is a multifunctional transglutaminase with a significant role in hemostasis. FXIIIa catalyzes the last step in the coagulation process. It stabilizes the blood clot by cross-linking the α- and γ-chains of fibrin. It also protects the newly formed clot from plasmin-mediate...

詳細記述

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書誌詳細
出版年:Eur J Med Chem
主要な著者: Al-Horani, Rami A., Kar, Srabani
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7513741/
https://ncbi.nlm.nih.gov/pubmed/32502864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.112442
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