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Potential Therapeutic Roles for Direct Factor Xa Inhibitors in Coronavirus Infections
Human factor Xa (FXa) is a serine protease of the common coagulation pathway. FXa is known to activate prothrombin to thrombin, which eventually leads to the formation of cross-linked blood clots. While this process is important in maintaining hemostasis, excessive thrombin generation results in a h...
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| Udgivet i: | Am J Cardiovasc Drugs |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer International Publishing
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7486161/ https://ncbi.nlm.nih.gov/pubmed/32918208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40256-020-00438-6 |
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