PTEN Loss Shapes Macrophage Dynamics in High-Grade Serous Ovarian Carcinoma

High-grade serous ovarian carcinoma (HGSC) remains a disease with poor prognosis that is unresponsive to current immune checkpoint inhibitors. Although PI3K pathway alterations, such as PTEN loss, are common in HGSC, attempts to target this pathway have been unsuccessful. We hypothesized that aberra...

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Detaylı Bibliyografya
Yayımlandı:Cancer Res
Asıl Yazarlar: Spear, Sarah, Le Saux, Olivia, Mirza, Hasan B., Iyer, Nayana, Tyson, Katie, Grundland Freile, Fabio, Walton, Josephine B., Woodman, Chloé, Jarvis, Sheba, Ennis, Darren P., Aguirre Hernandez, Carmen, Xu, Yuewei, Spiliopoulou, Pavlina, Brenton, James D., Costa-Pereira, Ana P., Cook, David P., Vanderhyden, Barbara C., Keun, Hector C., Triantafyllou, Evangelos, Arnold, James N., McNeish, Iain A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Association for Cancer Research 2024
Konular:
Cancer Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616669/
https://ncbi.nlm.nih.gov/pubmed/39186679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-23-3890
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