Restoring Agonist Function at a Chemogenetically Modified M(1) Muscarinic Acetylcholine Receptor

Designer receptors exclusively activated by designer drugs (DREADDs) have been successfully employed to activate signaling pathways associated with specific muscarinic acetylcholine receptor (mAChR) subtypes. The M(1) DREADD mAChR displays minimal responsiveness to the endogenous agonist acetylcholi...

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Xehetasun bibliografikoak
Argitaratua izan da:ACS Chem Neurosci
Egile Nagusiak: Khajehali, Elham, Bradley, Sophie, van der Westhuizen, Emma T., Molloy, Colin, Valant, Celine, Finlayson, Lisa, Lindsley, Craig W., Sexton, Patrick M., Tobin, Andrew B., Christopoulos, Arthur
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616161/
https://ncbi.nlm.nih.gov/pubmed/33196174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00540
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