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Restoring Agonist Function at a Chemogenetically Modified M(1) Muscarinic Acetylcholine Receptor
Designer receptors exclusively activated by designer drugs (DREADDs) have been successfully employed to activate signaling pathways associated with specific muscarinic acetylcholine receptor (mAChR) subtypes. The M(1) DREADD mAChR displays minimal responsiveness to the endogenous agonist acetylcholi...
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| Udgivet i: | ACS Chem Neurosci |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7616161/ https://ncbi.nlm.nih.gov/pubmed/33196174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00540 |
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