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Single-molecule magnetic tweezers to probe the equilibrium dynamics of individual proteins at physiologically-relevant forces and timescales

The reversible unfolding and refolding of proteins is a regulatory mechanism of tissue elasticity and signalling, used by cells to sense and adapt to extracellular and intracellular mechanical forces. However, most of these proteins exhibit low mechanical stability, posing technical challenges to th...

詳細記述

保存先:
書誌詳細
出版年:Nat Protoc
主要な著者: Tapia-Rojo, Rafael, Mora, Marc, Garcia-Manyes, Sergi
フォーマット: Artigo
言語:Inglês
出版事項: 2024
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616092/
https://ncbi.nlm.nih.gov/pubmed/38467905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-024-00965-5
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