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Multiplexed Single-molecule Force Proteolysis Measurements Using Magnetic Tweezers

The generation and detection of mechanical forces is a ubiquitous aspect of cell physiology, with direct relevance to cancer metastasis(1), atherogenesis(2) and wound healing(3). In each of these examples, cells both exert force on their surroundings and simultaneously enzymatically remodel the extr...

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Main Authors: Adhikari, Arjun S., Chai, Jack, Dunn, Alexander R.
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479978/
https://ncbi.nlm.nih.gov/pubmed/22871786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3520
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