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IL-2-driven CD8(+) T cell phenotypes: implications for immunotherapy

The therapeutic potential of interleukin (IL)-2 in cancer treatment has been known for decades, yet its widespread adoption in clinical practice remains limited. Recently, chimeric proteins of an anti-PD-1 antibody and suboptimal IL-2 variants were shown to stimulate potent antitumor and antiviral i...

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Detalhes bibliográficos
Publicado no:Trends Immunol
Main Authors: Niederlova, Veronika, Tsyklauri, Oksana, Kovar, Marek, Stepanek, Ondrej
Formato: Artigo
Idioma:Inglês
Publicado em: 2023
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615502/
https://ncbi.nlm.nih.gov/pubmed/37827864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2023.09.003
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