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An intense form of homeostatic proliferation of naive CD8(+) cells driven by IL-2

In conditions of T lymphopenia, interleukin (IL) 7 levels rise and, via T cell receptor for antigen–self–major histocompatibility complex (MHC) interaction, induce residual naive T cells to proliferate. This pattern of lymphopenia-induced “homeostatic” proliferation is typically quite slow and cause...

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Detalhes bibliográficos
Main Authors: Cho, Jae-Ho, Boyman, Onur, Kim, Hee-Ok, Hahm, Bumsuk, Rubinstein, Mark P., Ramsey, Chris, Kim, David M., Surh, Charles D., Sprent, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118670/
https://ncbi.nlm.nih.gov/pubmed/17664294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070740
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