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Converting IL-15 to a superagonist by binding to soluble IL-15Rα
IL-15 is normally presented in vivo as a cell-associated cytokine bound to IL-15Rα. We show here that the biological activity of soluble IL-15 is much improved after interaction with recombinant soluble IL-15Rα; after injection, soluble IL-15/IL-15Rα complexes rapidly induce strong and selective exp...
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| Main Authors: | , , , , , , |
|---|---|
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
National Academy of Sciences
2006
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1482584/ https://ncbi.nlm.nih.gov/pubmed/16757567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600240103 |
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