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Design and characterization of a protein superagonist of IL-15 fused with IL-15Rα and a high-affinity T cell receptor
To avoid high systemic doses, strategies involving antigen-specific delivery of cytokine via linked antibodies or antibody fragments have been employed. Targeting cancer-associated peptides presented by MHC molecules (pepMHC) increases the number of potential target antigens, and takes advantage of...
Bewaard in:
| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3514595/ https://ncbi.nlm.nih.gov/pubmed/22961781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btpr.1631 |
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