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T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity

The interaction between the T-cell receptor (TCR) and its peptide–major histocompatibility complex (pepMHC) ligand plays a critical role in determining the activity and specificity of the T cell. The binding properties associated with these interactions have now been studied in many systems, providi...

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Detalhes bibliográficos
Main Authors: Stone, Jennifer D, Chervin, Adam S, Kranz, David M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632691/
https://ncbi.nlm.nih.gov/pubmed/19125887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.03015.x
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