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The Impact of TCR-Binding Properties and Antigen Presentation Format on T Cell Responsiveness
TCR interactions with cognate peptide-MHC (pepMHC) ligands are generally low affinity. This feature, together with the requirement for CD8/CD4 participation, has made it difficult to dissect relationships between TCR-binding parameters and T cell activation. Interpretations are further complicated w...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841305/ https://ncbi.nlm.nih.gov/pubmed/19553539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900054 |
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