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Design of T cell receptor libraries with diverse binding properties to examine adoptive T cell responses
Adoptive T cell therapies have shown significant promise in the treatment of cancer and viral diseases. One approach, that introduces antigen-specific T cell receptors (TCRs) into ex vivo activated T cells, is designed to overcome central tolerance mechanisms that prevent responses by endogenous T c...
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| Publicado no: | Gene Ther |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5330764/ https://ncbi.nlm.nih.gov/pubmed/23052828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2012.80 |
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