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A novel T cell receptor single-chain signaling complex mediates antigen-specific T cell activity and tumor control
Adoptive transfer of genetically modified T cells to treat cancer has shown promise in several clinical trials. Two main strategies have been applied to redirect T cells against cancer: (1) introduction of a full-length T cell receptor (TCR) specific for a tumor-associated peptide—MHC, or (2) introd...
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| Publicado no: | Cancer Immunol Immunother |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4262137/ https://ncbi.nlm.nih.gov/pubmed/25082071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-014-1586-z |
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