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Engineering higher affinity T cell receptors using a T cell display system
The T cell receptor (TCR) determines the cellular response to antigens, which are presented on the surface of target cells in the form of a peptide bound to a product of the major histocompatibility complex (pepMHC). The response of the T cell depends on the affinity of the TCR for the pepMHC, yet m...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680719/ https://ncbi.nlm.nih.gov/pubmed/18854190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2008.09.016 |
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