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IL-2/anti-IL-2 mAb immunocomplexes: A renascence of IL-2 in cancer immunotherapy?

The in vivo biological activity of IL-2 can be dramatically increased by complexing with anti-IL-2 mAb. Moreover, IL-2/anti-IL-2 mAb immunocomplexes selectively stimulate different subsets of immune cells, depending on the clone of anti-IL-2 mAb that is used. Thus, IL-2/S4B6 mAb complexes strongly s...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Tomala, Jakub, Kovar, Marek
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839359/
https://ncbi.nlm.nih.gov/pubmed/27141363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1102829
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