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Combined IL-2 Immunocomplex and Anti-IL-5 mAb Treatment Expands Foxp3(+) Treg Cells in the Absence of Eosinophilia and Ameliorates Experimental Colitis
Interleukin (IL)-2 is expressed during T cell activation and induces the proliferation and differentiation of T cells. CD4(+)Foxp3(+) regulatory T cells (Tregs) constitutively express the high affinity IL-2 receptor (CD25/IL-2Rα) and rapidly respond to IL-2 to elaborate numerous suppressive mechanis...
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| Gepubliceerd in: | Front Immunol |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Frontiers Media S.A.
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6428029/ https://ncbi.nlm.nih.gov/pubmed/30930900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00459 |
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